Early deep anterior lamellar keratoplasty for fungal keratitis poorly responsive to medical treatment.
PurposeTo investigated the efficacy of initial therapy in anterior lamellar keratoplasty (DALK) in combating fungal keratitis were less responsive to medical treatment.Patients and methodsTwenty-three eyes (23 patients) underwent DALK start of therapy within 15 to 50 days of onset of symptoms. DALK eligibility criteria adopted early include the following: active fungal keratitis affects the optical zone with limited ulcers at 6:00 mm central cornea; more than 150 m but not more than 300 m; and less responsive to medical treatment.ResultsThe big bubble technique achieved in 74% (17) of the eye, while the user dissection is done in the remaining 26% (6) of the eye.
Histopathological examination showed no signs of fungal colonization in the peripheral and deep stroma lamella in any case. All postoperative graft is transparent, and no recurrence of infection. Median best spectacle corrected visual acuity was significantly increased from 2.0 (interquartile range 1.0) to 0.1 logMAR (0.1 interquartile range) logMAR (P <0.01). Mean follow-up was 32 ± 10 months. Both episodes of rejection or graft failure was recorded during follow-up period.ConclusionEarly DALK could represent a safe therapy to eradicate fungal keratitis affecting the optical zone and less responsive to medical treatment.
stimulus-responsive polymers have been used to improve the efficacy of medical diagnosis through different approaches including increasing the contrast in imaging techniques and promote the recognition molecules in diagnostic tests. This review an overview of the mechanisms of stimulus-responsive polymer in response to external stimuli, including temperature, pH, ions, light, etc. responsive polymer applications in magnetic resonance imaging, capture and purification of biomolecules through recognition and lab-on protein-ligand -a-chip technology is discussed.
primitive neuroectodermal kidney tumor with inferior vena cava thrombosis and both responsive to the medical and surgical treatment: description of a case and literature revision.
Primitive neuroectodermal tumor (PNET) of the kidney is a rare cancer typical of young adults with few cases described in the literature. We report a case of renal PNET on a 31-year-old man presented to our department with computed tomography (CT) revealed -Scan large renal mass 20 cm, thrombosis of the inferior vena cava (IVC). The patient underwent radical nephrectomy with contextual retroperitoneal lymphadenectomy and resection of IVC require substitution Dacron prosthesis.
The definitive histopathological examination showed renal PNET infiltrated the ipsilateral adrenal gland, great cava vena cava thrombosis with infiltration of the wall and the lymph nodal metastasis. Postoperative PET scan showed metastatic lesions in bilateral adrenal glands and pancreas. Patients receiving chemotherapy, and this time, he was in follow-up after the first 26 months of diagnosis without signs of disease recurrence. PNET kidneys usually associated with a poor prognosis, thus, need early identification and differentiation of tumor cells of other similar small to get a good response to treatment.
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Description: S-adenosylmethionine ELISA kit |
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Description: S-adenosylhomocysteine ELISA kit |
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This review outlines the various health problems that occur in brain injury patients in a coma or emerging from coma, including patient population vegetative and minimally responsive. This range of medical problems including those related to the original injury or brain-related injury, they represent a complication of bedrest, and caused by the use of drugs that may inhibit recovery or contribute to obtunded state or coma.